File:Epistasis and landscapes.png

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DescriptionEpistasis and landscapes.png	English: The top row indicates interactions between two genes that are either additive (a), show positive epistasis (b) or reciprocal sign epistasis (c). Below are fitness landscapes which display greater and greater levels of global epistasis between large numbers of genes. Purely additive interactions lead to a single smooth peak (d), as increasing numbers of genes exhibit epistasis, the landscape becomes more rugged (e) and when all genes interact epistatically the landscape becomes so rugged that mutations have seemingly random effects (f).
Date	20 December 2013, 21:31:19
Source	Thomas, Shafee, (2014). "Evolvability of a viral protease: experimental evolution of catalysis, robustness and specificity". PhD Thesis. University of Cambridge.
Author	Thomas Shafee

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	Date/Time	Thumbnail	Dimensions	User	Comment
current	10:41, 20 December 2013		967 × 788 (326 KB)	Evolution and evolvability	User created page with UploadWizard

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